Melanie Cree, [associate professor of pediatrics at CU School of Medicine,] director of the University of Colorado’s PCOS multidisciplinary clinic and pediatric endocrinologist at Children’s Hospital Colorado, is the main investigator on a clinical trial testing semaglutide in 80 obese girls and women with PCOS aged 12 to 35. She explains how GLP-1 drugs are thought to encourage ovulation in the condition.