Ozempic was supposed to be a gut story. Then Allison Shapiro looked at the brain scans. An assistant professor at the University of Colorado Anschutz, she was part of a team studying 13 teens and young women with a hormonal disorder affecting the ovaries who were put on GLP-1 drugs. As part of testing to catalogue the effect of the medication on their bodies, Shapiro took snapshots of their brains before and after. She was astonished to find extensive changes.