Boston-based Massachusetts General Hospital was the highest-performing U.S. healthcare institution on Nature‘s 2026 Research Leaders ranking. Nature used research output data from 178 publications between Jan. 1, 2025, and Dec. 31, 2025, to assess organizations’ research quality and institutional performance. Read Nature’s full methodology here. The top 25 U.S. healthcare institutions for research in 2025 were, according to Nature:
11. University of Colorado Anschutz Medical Campus (Aurora)