CU Anschutz In The News

"An oncogene called MYC is amplified in these tumors making them very susceptible to recurrence. In addition, there's a greater risk of it spreading to other areas of the brain and down the spine," said Siddhartha Mitra, Ph.D., assistant professor of Hematology-Oncology and Bone Marrow Transplant at the University of Colorado School of Medicine and University of Colorado Cancer Center member. "The five-year survival rate of this cancer is less than 45 percent. We wanted to discover better treatment options for these kids."

A newer technique for preparing corneal tissue for transplantation has been shown to be safe and effective, while providing a faster and smoother process than the traditional technique, according to researchers in the Department of Ophthalmology at University of Colorado School of Medicine.

"Our findings indicate that ulceration is an independent predictor of the three known features experts use in risk stratification of GISTs," says Martin McCarter, MD, corresponding author and member of the CU Cancer Center. "This finding is significant because it's new information that might change the future of treatment of this tumor."

"The term 'ableism' is not as well-known as the term 'racism' but it is a concept that is underrecognized in medicine," said essay author Megan Morris, Ph.D., MPH, an associate professor at the University of Colorado School of Medicine who focuses on health disparities among those with disabilities. "The health care system is not set up to deal with this population who is at serious risk for experiencing disparities."

"We know that abnormalities in the large vessels around the heart, the aorta and its primary branches, begin to develop in early childhood in people with Type 1 diabetes," said lead study author Michal Schäfer, Ph.D., a researcher and fourth-year medical student at the University of Colorado School of Medicine in Aurora, Colorado. "We found that bromocriptine has the potential to slow down the development of those abnormalities and decrease the risk for cardiovascular disease in this population."

In a new paper published in Clinical Lung Cancer, physicians and researchers at the CU Cancer Center share their experience with pregnancies and other pathways to motherhood in women with oncogene-driven lung cancer. The Center, located on the University of Colorado Anschutz Medical Campus, is recognized as one of the most sought after cancer centers in the world for patients receiving targeted therapy for lung cancer, including those interested in pursuing motherhood.

"We performed a large dataset analysis and demonstrated that administering midazolam is associated with an increased risk of myocardial injury in non-cardiac surgery when surgeries occurred at night and in healthier patients," said the study's senior author Tobias Eckle, MD, Ph.D., professor of anesthesiology at the University of Colorado School of Medicine. "This is significant because these findings could have tremendous implications for patient mortality."

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus.