Anschutz Cancer Pavilion
1665 North Aurora Court
Aurora, CO 80045
Although rare, kidney cancer is the third most common type of solid tumor affecting children. Thankfully, pediatric kidney tumors are generally treatable and most have high cure rates. Treatment outcomes depend on several factors including age, tumor type, staging, genetics, the overall health of the patient, and the risk of treatment side effects.
A new phase 3 randomized clinical trial overseen by CU Cancer Center member Chad Rusthoven, MD, and Vinai Gondi, MD, from Northwestern University, is testing whether a new treatment approach could result in improved outcomes for patients with small cell lung cancer (SCLC) that has spread to the brain.
A team of University of Colorado School of Medicine researchers recently published a paper offering new insight into the role that oxygen deprivation, or hypoxia, plays in cancer development. CU Cancer Center member Joaquin Espinosa, PhD, is the senior researcher on the paper, which he hopes will help lead to more targeted treatments for cancer.
M. Eric Kohler’s commitment to both cancer research — particularly CAR T-cell therapy — and clinical care make him a double threat when it comes to battling pediatric blood cancer.
Though breast cancer patients are now living longer than ever before, treatments for the disease can have wide-ranging effects on their long-term quality of life. Physical, social, and sexual wellbeing all can be impacted by radiation, chemotherapy, surgery, antiendocrine therapy and other challenges that go along with a breast cancer battle.
Sabrina L. Spencer, PhD, is a CU Boulder researcher and a CU Cancer Center member. Spencer recently won two awards: the Damon Runyon-Rachleff Innovation Award (from the Damon Runyon Cancer Research Foundation) and the Emerging Leader Award (from The Mark Foundation for Cancer Research). The preliminary research she used to apply for the grants, "Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling," was published in Nature Communications on March 19, 2021.
We spoke to Spencer about the awards and how she plans to use them to further her research.
Three University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the immune system relates to cancer. Quentin Vicens, PhD, Jeffrey Kieft, PhD, and Beat Vögeli, PhD, are authors on the paper, which looks at how an enzyme called ADAR1 operates in pathways associated with cancer.
A multiyear grant totaling $500,000 is aimed at making the University of Colorado Cancer Center even better at providing multidisciplinary care for patients with pancreatic cancer.
Ashton Villars has always been a problem solver. As a competitive athlete in basketball, waterskiing, and tennis and an actual rocket scientist, Villars has tackled every challenge in life head on — including his prostate cancer diagnosis. Now, he’s bringing that same problem-solving spirit to supporting cancer research.
Three projects from University of Colorado Cancer Center researchers have received grants from the Denver-based Michele Plachy-Rubin Fund for Pilot Grants in Brain Cancer Research. Receiving $40,000 each to fund their work around brain cancer are Sujatha Venkataraman, PhD; and the teams of Philip Reigan, PhD, and Michael Graner, PhD; and Natalie Serkova, PhD, and Nicholas Foreman, MD, MBChB.
For more than a year, a working group at the University of Colorado Cancer Center has been studying the many ways the aging process impacts cancer — including incidence, progression, and prognosis of the disease, therapeutic options and outcomes, and the psychosocial aspects of living with cancer.
The Denver chapter of Golfers Against Cancer this week named University of Colorado (CU) Cancer Center researchers Matthew Sikora, PhD, Jamie Studts, PhD, and Jenna Sopfe, MD, as the beneficiaries of three $50,000 grants for cancer research and clinical trials.
At the University of Colorado (CU) Cancer Center, we use awareness months and days to highlight and honor our patients – both past and present – that have fought these cancers, as well as educate about warning signs, new treatments, clinical trials, prevention methods, and support options.
Actor Dustin Diamond, best known for playing the nerdy character Screech on teen sitcom “Saved By the Bell,” died Monday at age 44. Diamond died just weeks after being diagnosed with stage 4 small cell carcinoma, a type of cancer that commonly occurs in the lungs but can also originate in the prostate or gastrointestinal tract.
For the past 20 years, the Union for International Cancer Control has designated February 4 as World Cancer Day — a day to raise awareness, improve education, and catalyze personal, collective, and government action around the deadly disease. The organization hopes to reduce the number of premature deaths from cancer and noncommunicable diseases by one-third by 2030.
January is Cervical Cancer Awareness Month, and CU Cancer Center member Lindsay Brubaker, MD, wants everyone to be aware of the relationship between cervical cancer and the human papillomavirus (HPV), a sexually-transmitted disease that causes the vast majority of cervical cancers. The current HPV vaccine protects against seven predominant strains of the virus that cause cancer, as well as the two that cause genital warts.
New research from CU Cancer Center member Jing Hong Wang, MD, PhD, and recent University of Colorado Immunology program graduate Rachel Woolaver, PhD, may help researchers develop more effective personalized immunotherapy for cancer patients.
There’s never a good time for a cancer diagnosis, but it’s especially difficult in the middle of a pandemic, when concerns about safety compound the worry and anxiety that come along with hearing, “you have cancer.”
A 13-year veteran of the National Cancer Institute (NCI) is coming to the University of Colorado Cancer Center to help lead efforts to develop and apply data science and artificial intelligence and methods to advance research and improve clinical practice.
The global pandemic of 2020 has been a pivotal year for the health care industry. This year lead some CU Cancer Center members to shift their focus to learning more about COVID-19 while others continued their research on cancer. Whether the focus was on COVID-19 or Cancer this year showed how coming together as a community can make a difference.
COVID-19 is the most-talked-about health concern in 2020, but for many, it is not the deadliest disease. University of Colorado (CU) Cancer Center leadership is bringing attention to the fact that more people will die from cancer than COVID this year.
Like most people, Arnette Schouten has been touched personally by cancer. One of her cousins is in hospice following a battle with melanoma; her sister-in-law had a long fight with breast cancer; and Arnette herself had early symptoms of ovarian cancer that were caught in time for effective treatment.
The past year has illuminated the need for change. In addition to the toll it has taken on lives, health and livelihood, COVID-19 has shed light on health disparities and inequities facing our communities of color.
Elissa Kolva, PhD, clinical psychiatrist and CU Cancer Center member, shares tips that might be helpful for caregivers during the COVID-19 pandemic.
Until you or a loved one are facing treatment for a cancer diagnosis, you may not realize the cost associated with treatment and doctor visits. Unfortunately, the cost is continuing to rise as new treatments are discovered and patients are responsible for more of those costs, even if they have health insurance coverage.
Craig Jordan, PhD, has spent more than 20 years developing better treatments for acute myeloid leukemia (AML), a rapidly progressing cancer of the blood and bone marrow that can spread to other parts of the body, including the lymph nodes, liver, spleen and central nervous system.
Longtime “Jeopardy!” host Alex Trebek announced it to the world on March 6, 2019: Like 50,000 other Americans each year, he had been diagnosed with stage 4 pancreatic cancer.
Thanks in large part to early work by investigators at the CU Cancer Center, patients with acute myeloid leukemia (AML) have a new treatment option that has fewer side effects and has been shown to increase longevity.
A new movie streaming on Disney+ is shining a spotlight on a rare type of bone cancer that occurs most often in children and young adults.
In the 1860s, French physician Armand Trousseau noticed that patients with a certain form of abnormal blood clotting often went on to be diagnosed with pancreas or gastric cancers. Unfortunately, at age 66 he noticed these same symptoms in himself and died of gastric cancer only a few months later.
Studies have long reported that Black cancer patients have poorer outcomes than their white counterparts. But two University of Colorado Cancer Center researchers decided to investigate the data further and figure out why. What they found was that the outcome disparity was caused not by biology, but simply by differences in access to health care.
A consortium of 17 cancer centers around the country have come together to better understand the consequences of the COVID-19 pandemic as it relates to delayed cancer detection, care and prevention.
By now, we’ve all heard about the importance of cancer screening. But for those with a detected cancer, a new article highlights that the removal of the malignancy might not be where you should stop in your health journey.
After nearly four years of work, a group of researchers and clinicians from the University of Colorado (CU) published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response.
Siri Lindley couldn’t swim. She had never learned how. So the idea of competing in a triathlon seemed completely out of the question.
“I couldn’t help but fall in love with the sport,” says Siri. “Something about it drew me in and I knew I had to start training.”
Last month the American Cancer Society (ACS) released updated guidelines for cervical cancer screening. The most notable change in guidelines is the changes in the age to begin screening. Per the new guidelines, it is recommended that cervical cancer screening begin at age 25. Previously, the starting age for screening was 21.
As survival rates of many common cancers have improved it is no surprise that conversations around fertility preservation have also increased. These advances in treatments are letting patients think about their future beyond cancer, and if that future includes children.
A key component in treating newly diagnosed leukemia is genetic and molecular testing. With this knowledge, physicians can better determine which treatment options are best suited for patients based on genetic mutations, fusions and other biologic features.
Black and Hispanic children diagnosed with brain and central nervous system (CNS) cancers have worse outcomes than their white counterparts in the United States. The reasons behind this are unclear but may include socioeconomic factors and/or limited access to quality care. Now, researchers at the University of Colorado (CU) Cancer Center and Children’s Hospital Colorado on the Anschutz Medical Campus are collaborating to better understand these disparities, as well as develop ways to reduce the burden of disease in these populations.
University of Colorado Cancer Center member and associate professor of Pathology Paul Jedlicka, MD, PhD, has received the St. Baldrick’s Research Grant with generous support from Marlee’s Smile. His research will focus on better understanding the mechanisms behind rhabdomyosarcoma, a common and aggressive cancer type in children. The goal of the research is to identify new approaches to interfering with disease progression.
On July 23rd, Richard Schulick, MD, MBA, director of the University of Colorado (CU) Cancer Center, Cathy Bradley, PhD, deputy director of the CU Cancer Center, James DeGregori, PhD, deputy director of the CU Cancer Center, took part in a virtual panel that highlighted the impact of COVID-19 on cancer as well as the ways the CU Cancer Center is redefining cancer care. The panel was moderated by Don Elliman, Chancellor of the Anschutz Medical Campus.
The American Cancer Society recently updated its recommendation from limiting alcohol to avoiding alcohol altogether to reduce cancer risk. Here, the University of Colorado Cancer Center discusses this update with Valaree Williams, MS, RD, CSO, CNSC, FAND, lead dietician from the Oncology Supportive Services at UCHealth.
Cecilia Caino, PhD, has been researching cancer cell biology at University of Colorado Cancer Center since 2017. Cecilia earned her PhD in Cellular Biology from the University of Buenos Aires with her research component performed at the University of Pennsylvania, and completed a postdoctoral fellowship at The Wistar Institute. We spoke with Dr. Caino about her research on how cancer cells use energy and how their unique energy strategies could help cancer cells spread.
In the midst of a global pandemic, it seems odd to be asking my 18-year-old neighbor about the dangers of vaping. However, keeping a safe six-foot distance away and wearing homemade masks, we’re able to hold a decent conversation across the front lawn. My question is simple: Is vaping dangerous? His answer: “I don’t know, but I think it is safer than smoking a cigarette.”
“Have you ever had a dream when you wake up and everything is just kind of vibrating? It doesn’t make any sense but it kind of points the way?” asks Fort Collins artist and musician, Shelley Kerr.
In July 2019, Emily McClintock Addlesperger was on vacation in Maine with her husband, Jason, when she felt sick and was airlifted to Portland with internal bleeding. A tumor on her ovary had burst. It was Monday. On Saturday, she passed away. Emily was 44 years old.
January 2020 was unseasonably warm and dry, so pleasant that students on the Anschutz Medical Campus ate lunch at picnic tables and scientists emerged confused and squinting from hibernation in the campus research buildings. One person who was not there was Deguang Kong, visiting graduate student in the lab of Heide Ford, PhD, University of Colorado (CU) Cancer Center Associate Director for Basic Research. With his PhD work wrapping up, Deguang had taken a quick leave to interview for jobs near his home…in Wuhan, China.
Telemedicine is not a new concept. However, due to the coronavirus pandemic, it might not be something that many providers or patients are becoming familiar with. Recently, it was announced that over 200,000 virtual primary care and specialty visits have occurred since the start of the pandemic at UCHealth, where University of Colorado (CU) Cancer Center doctors provide care.
While runs and galas that raise money for many different causes have been affected by COVID-19 there is one fundraising event that is made for social distancing, rappelling down a building. The Over the Edge event by the Cancer League of Colorado (CLC) is doing just that while raising money for Colorado based cancer research.
Many patients diagnosed with COVID-19 have symptoms such as a persistent dry cough, shortness of breath, and in some cases, incredibly low oxygen levels in their blood. Additionally, many patients report having long-lasting side effects, for example decreased lung capacity, even after they recover from the virus.
Originally posted on the University of Colorado (CU) Department of Psychiatry website. Tips from Joanna Arch, PhD, associate professor in the Department of Psychology and Neuroscience and CU Cancer Center member.
In late 2019, two remarkable women were brought together by a shared experience that could only happen at the University of Colorado Anschutz Health & Wellness Center. Through their participation in the BFitBWell Program for cancer survivors, they found renewed strength and friendship.
Nearly two thousand people living in Colorado will be diagnosed with head and neck cancer (HNC) in 2020. Generally, a very aggressive disease, head and neck cancer require expert care that is not widely available in community cancer clinics. However, patients that are not well-represented in clinical studies, especially Hispanic patients, are less likely to get care from centers that specialize in the disease, such as the University of Colorado Cancer Center.
Lung cancer is the deadliest cancer in the United States. In Colorado more than 2,500 people will be diagnosed with the disease and more than 1,400 will die of it in 2020. While advances in lung cancer treatment have gifted many patients with more time, the benefit of these treatments is limited by the racial and socioeconomic status of some patients in Colorado. A new study at the University of Colorado Cancer Center focuses on reducing disparities in lung cancer patients with diverse backgrounds.
While many cancer types have added new treatments including genetically targeted drugs and immunotherapies, treatment for the rare types of cancer known as sarcomas have remained largely the same for about two decades. Now, two grants to University of Colorado Cancer Center researchers from the Sarcoma Foundation of America hope to change this.
U.S. News and World Report (USNWR) released its 2020-21 Best Children’s Hospitals rankings this week. In the category of best hospitals for pediatric cancer, Children’s Hospital Colorado was ranked ninth in the country. Pediatric cancer services are provided by University of Colorado (CU) School of Medicine faculty who many are members of the CU Cancer Center.
University of Colorado (CU) researcher Srinivas Ramachandran, PhD, was named one of the five 2020 Pew-Stewart Scholars. These researchers are selected to spearhead innovations in cancer research.
University of Colorado radiation oncologist Chad Rusthoven, MD, was recently awarded the prestigious Dr. Charles A. Coltman Jr. research fellowship award from the Hope Foundation for Cancer Research. The award provides two years of salary support to engage early career investigators from Southwest Oncology Group (SWOG) affiliated institutions in clinical trial research.
When a cancer patient needs a bone marrow transplant, there are four common donor sources: A matched related donor (sibling), a matched unrelated donor (from a donor database), a half-matched donor, or umbilical cord blood. Of course, there are plusses and minuses to each approach, but consensus has generally ranked a matched sibling first, followed by a matched unrelated donor, with cord blood and half-matched donors reserved for patients without either of the first two options. Now a University of Colorado Cancer Center study based on a decade of research and treatment may reshuffle this list. In fact, the comparison of 190 patients receiving cord-blood transplants with 123 patients receiving transplants from the “gold standard” of matched sibling donors showed no difference in survival outcomes between these two approaches, with significantly fewer complications due to chronic graft-versus-host disease in patients receiving transplants from cord blood.
The international First-line Radiosurgery for Small-Cell Lung Cancer (FIRE-SCLC) analysis led by University of Colorado Cancer Center researchers and published today in JAMA Oncology details clinical outcomes for 710 patients with brain metastases from small cell lung cancer treated with first-line stereotactic radiosurgery (SRS), without prior treatment with whole-brain radiation (WBRT) or prophylactic cranial irradiation (PCI).
Results of the phase III Inter-B-NHL-ritux 2010 clinical trial reported today in the New England Journal of Medicine show 95 percent three-year survival for pediatric patients with advanced B-cell non-Hodgkin lymphoma treated with the addition of anti-cancer immunotherapy rituximab to standard chemotherapy. The trial represents a major international collaboration between the European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) and the Children’s Oncology Group (COG), and was led in the United States by Thomas Gross, MD, PhD, University of Colorado Cancer Center investigator and pediatric oncologist at Children’s Hospital Colorado, and in Europe by Véronique Minard-Colin, MD and Catherine Patte, MD, both pediatric oncologists at the Gustave Roussy Department of Child and Adolescent Oncology in Paris, France. The addition of rituximab decreased treatment failures by 70 percent resulting in a 10 percent increase in the three-year survival rate seen with chemotherapy alone (LMB protocol).
From Barbara Wenger, breast cancer survivor:
In mid-March, the University of Colorado Cancer Center Cell Technologies Shared Resource shut down along with almost all the other labs and technologies on the Anschutz Medical Campus. Then shared resource director, Steve Anderson, PhD, got an email from a colleague asking if the facility could make COVID-19 proteins. They could: The shared resource has been making proteins for over 15 years.
In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question has become what cocktail and sequence is best?
In the summer of 2019, Dr. Neil Box toured Colorado with the Sun Bus, attending events with over 700,000 participants and reaching 26,000 people in 46 service days. Free skin cancer screens identified 96 suspected skin cancers, including six cases of dangerous melanoma. The tour also gave Dr. Box the opportunity to hear what people think about skin cancer and sun protection.
One of the few labs on the Anschutz Medical Campus to remain mostly open during the COVID-19 shutdown is the University of Colorado Cancer Center Animal Imaging Shared Resource (AISR).
“For Christmas, we took a family photo with all the grandkids,” says Sam’s wife, Janet. She went on to explain, “The kids wanted to take this photo because they thought Sam would not be here next Christmas.”
You’ve heard of the Human Genome Project. Now the University of Colorado Cancer Center Human Immune Monitoring Shared Resource (HIMSR) is partnering with the Cancer Center Tissue Biobanking and Histology Shared Resource to store COVID-19 samples for individual research efforts and for a major project known as the COVID-ome.
During the COVID-19 pandemic patients with cancer may be experiencing mental health challenges such as increased anxiety or depression. The psycho-oncology team at the CU Cancer Center is providing tips that can help during these difficult times.
One of the major complications of severe COVID-19 is blood clots in the lungs – a pulmonary embolism that can block lung function leading to death. In fact, these blockages are similar to those from chronic heart disease, stroke, and even traumatic injuries like a car crash or gunshot wound. In these non-COVID-19 conditions, doctors use drugs to break up and dissolve the clotted blood. Now a team led by Colorado trauma surgeon Gene Moore, MD, is testing a similar approach against the dangerous blood clots associated with COVID-19.
French and Australian studies suggest the anti-malarial drug chloroquine could be effective against COVID-19. Promising early results now lead the U.S. Food and Drug Administration to fast-track its own tests, and have spurred the drug’s maker, Bayer, to offer the drug free for treatment. Earlier today, President Trump (among others) touted chloroquine as a ready-to-use treatment for the disease.
We should all be doing our best to keep from catching COVID-19, if not for ourselves and our loved ones, then to avoid passing the disease to people in high-risk populations – like cancer patients taking chemotherapy, which can lower white blood cell counts and undercut the effectiveness of remaining white blood cells, leaving these patients immunocompromised and less able to fight infections like COVID-19.
Peyton taught the world that ovarian cancer doesn’t just strike mothers and grandmothers. “She’s brought so much awareness to the disease through her advocacy,” said CU Cancer Center member Saketh Guntupalli, MD.
It is one of the most common types of leukemias in adults; however, the disease comprises only about 1% of all cancers. There are a variety of treatment options available for patients with AML, with more clinical trials evaluating new therapies in the pipeline. In this episode of the “CURE talks Cancer” podcast, we spoke with Dan Pollyea, from the University of Colorado Cancer Center, about these treatment options.
Mia and her parents shared their experience with RadFlix with FOX31. They explained that watching TV or a movie while getting radiation treatment was a game-changer. RadFlix was developed by Douglas Holt, MD, Brian Miller, PhD, and Sarah Milgrom, MD.
Bucky Dilts, former Denver Broncos and prostate cancer survivor, and Dr. Paul Maroni, shared with CBS Denver why men should be getting a prostate cancer screening.