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A combined polygenic score of 21,293 rare and 22 common variants improves diabetes diagnosis based on hemoglobin A1C levels

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Written by Nature on October 24, 2022

Polygenic scores (PGSs) combine the effects of common genetic variants to predict risk or treatment strategies for complex diseases. Adding rare variation to PGSs has largely unknown benefits and is methodically challenging. 

Topics: Press Coverage

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