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Gates Institute News and Stories


Pediatric Cancer    Blood Cancer    Leukemia    Cancer    Oncology    Cell and Gene Therapy    Medical Oncology    Hematology

Getting to Know Maureen O’Brien, MD, MS

Maureen O’Brien, MD, MS, recently joined the faculty of University of Colorado Anschutz School of Medicine as a visiting professor in the Department of Pediatrics Section of Hematology/Oncology and Bone Marrow Transplantation. With support from Gates Institute and in collaboration with colleagues leading the adult leukemia programs, O’Brien will develop and help lead a campuswide high-risk leukemia program. This program will facilitate the implementation of early-phase clinical trials for pediatric and adult leukemia, including cellular therapies developed with the Gates Institute.

Author Toni Lapp | Publish Date June 20, 2024
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Research    Cancer    Advancement    Cell and Gene Therapy

Nephrologist Aims to Explore CAR T Therapy for Solid Tumors

Chimeric antigen receptor (CAR) T-cell therapy has shown great promise in the treatment of certain leukemias and lymphoma, but results in solid tumors have not been as impressive.

Author Toni Lapp | Publish Date March 18, 2024
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Leukemia    Cancer    Clinical Research    Clinical Trials    Cell and Gene Therapy

New CAR T-Cell Trial Enrolling Patients at CU Anschutz

Enrollment has begun for a new phase 1 study of chimeric antigen receptor (CAR) T-cell therapy at UCHealth University of Colorado Hospital for adults with B-cell acute lymphoblastic leukemia (B-ALL). The trial is the first launched through the newly formed Gates Institute, and it will be the fourth for which the Gates Biomanufacturing Facility produces the CAR T product for research at CU Anschutz Medical Campus.

Author Toni Lapp | Publish Date July 13, 2023
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Gates Institute In the News

The Denver Post

CU studying use of patients’ own reprogrammed cells to attack cancer as alternative to more chemo

news outletThe Denver Post
Publish DateMarch 14, 2024

A study at University of Colorado’s Gates Institute on the Anschutz Medical Campus is looking at CAR-T in adult patients with acute lymphocytic leukemia, a cancer of the blood and bone marrow, whose first round of chemotherapy either failed or gave a disappointing response that suggests it won’t work for long, executive director Dr. Terry Fry said. (The institute is named for rubber manufacturer Charles C. Gates.)

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UC Davis News

UC Davis Graduating Student Poised to Help Those With Rare Condition

news outletUC Davis News
Publish DateDecember 12, 2023

Encouraged by his care team at the Colorado hospital to apply for an internship at the Gates Institute research lab, Mann spent this summer surrounded by researchers helping develop novel therapeutics for Ehlers-Danlos Syndrome (EDS). He worked on an experiment that used cells from EDS patients to grow skin samples for study. The lab is investigating the use of exosomes — secreted by most cells and present in tissues and body fluids — as a vehicle for therapeutic intervention.

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Colorado Bioscience Association

Building a Life Sciences Pipeline: Cell and Gene Therapy Momentum

news outletColorado Bioscience Association
Publish DateMarch 06, 2023

When you talk to Terry Fry, M.D., about why the Gates Institute is one of the best locations in the country to work in cellular and gene therapy, he has a lot of insight. As the executive director of the Gates Institute, a pediatric oncologist, and a pioneer in the development of chimeric antigen receptor (CAR)-T cell therapies, Dr. Fry has an intimate understanding of what it takes to get a drug from initial research phases to commercial manufacturing.

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Genetic Engineering & Biotechnology News

University Creates Innovative Model for Running a GMP Manufacturing Facility

news outletGenetic Engineering & Biotechnology News
Publish DateFebruary 08, 2023

The University of Colorado has adopted an innovative model for running an academic GMP manufacturing facility without extensive endowment funding. The Charles Gates Biomanufacturing Facility is one of only a few GMP facilities able to manufacture cell- and protein-based therapies for both academic researchers and industry.

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