News and Stories

It started in the early 1990s as a registry of patients with a heart condition. Today, data from more than 2,000 families with dilated cardiomyopathy is informing the next generation of therapies for this serious disease.

Together, cardiologist Luisa Mestroni, MD, and geneticist Matthew Taylor, MD, PhD, both professors in the Division of Cardiology at the University of Colorado School of Medicine, have helped thousands of patients in the clinic. They’ve also studied many of the over 50 genes associated with dilated cardiomyopathy (DCM). In the following Q&A, they explain their research and the gene therapy clinical trials that will be launching on the CU Anschutz Medical Campus during the first half of 2024.

Guest Contributor | February 20, 2024

Like your home’s plumbing system, if a “pipe” clogs or corrodes and bursts within your vascular system, it can create a destructive mess, even leading to an all-systems failure if not addressed. Constant, high-pressure flow weakens arteries, and can knock corrosive plaque loose, creating a dangerous barrier. The best way to prevent a blowout? Take care of your house.

Debra Melani | December 04, 2023

Using laboratory engineered tissue, scientists at the University of Colorado Anschutz Medical Campus have created a full thickness, biodegradable patch that holds the promise of correcting congenital heart defects in infants, limiting invasive surgeries and outlasting current patches.

David Kelly | November 27, 2023

Lohit Garg, MBBS, grew curious about the workings of the heart from a young age. His interest was tinged with personal heartache as he watched several family members battle cardiac disease, especially his grandfather.

Chris Casey | September 14, 2023

A promising new stroke drug that temporarily inhibits a key protein in the brain without causing lasting harm may significantly change the future treatment of cerebral and global ischemia, according to a new study by scientists at the University of Colorado Anschutz Medical Campus. 

David Kelly | May 23, 2023