“This study has the potential for major clinical impact,” commenters wrote in an accompanying editorial. Justin B. Searns, with the Sections of Hospital Medicine and Infectious Diseases at Children’s Hospital Colorado [and associate professor of pediatrics], and Sean T. O’Leary, also with the Section of Pediatric Infectious Diseases at Children’s Hospital Colorado in Aurora, Colorado, [and professor of pediatrics] wrote that “In the US, more than 70,000 infants are evaluated for fever within the first few months of life every year. If the cohorts presented here are a representative sample, close to half of these febrile infants would be considered to be at low risk for bacterial infection.”
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