CAR T cells: The last line of defense against childhood leukemia

While chemotherapy has been the standard of care for B-ALL, it is not always reliable as a long-term cure. “The problem is that in patients where the cancer came back or was resistant to those standard treatments, we have to resort to bone marrow transplant, which is very toxic,” said Terry Fry, an oncologist and Executive Director of the Gates Institute at the University of Colorado Anschutz Medical Campus.