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New Study Reveals Widespread Liver Dysfunction in Down Syndrome, Suggests Link to Diet

Crnic Institute findings published in Cell Reports highlight understudied abnormal liver function in people with Down syndrome and possible dietary interventions

by Yahoo News | January 22, 2026
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“Our data show that Down syndrome profoundly impacts hepatic metabolism,” says Kelly Sullivan, PhD, senior author and associate professor of Pediatrics at the University of Colorado Anschutz. “Importantly, we found that dietary fat intake can exacerbate or ameliorate these effects in the mouse models, suggesting that nutrition could play a key role in managing liver health in this population.”