Obesity Drugs Ease PMOS Symptoms in Small Trials, but Insurance Denials Keep Many Patients from Getting Them

Melanie Cree, a professor at the University of Colorado Anschutz Medical Campus, has led three studies testing GLP-1 drugs for the condition. Early data from one of them, published in June in the journal Fertility and Sterility, reported that eight of eleven participants who completed the trial lost at least 10 percent of their body weight. Among those participants, the median weight loss was about 42 pounds, and the median drop in testosterone was 52 percent. Six women had more frequent periods, and four returned to monthly cycles.