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CU Cancer Center News and Stories

DNA

Research    Breast Cancer    DNA   

Researchers Find Less Risky Way to Monitor Breast Cancer Progression

Researchers at the University of Colorado Anschutz Medical Campus have discovered how to extract critical information about breast cancer tumors and disease progression by analyzing blood plasma rather than using more invasive tissue biopsies.

“This is simply a blood draw,” said the study’s senior co-author Peter Kabos, MD, associate professor of medicine in the medical oncology division at the University of Colorado School of Medicine and CU Cancer Center member. “This allows us to look under the surface to see the defining characteristics of the disease. The advantage is that we don’t need to do repeated tissue biopsies.”


Author David Kelly | Publish Date August 25, 2022
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Cancer    DNA    Irinotecan    AZD0156

Irinotecan breaks cancer cell DNA – AZD0156 keeps the body from repairing it

The chemotherapy drug irinotecan creates DNA damage leading to cell death and is used to treat colorectal cancer, among other cancer types. Now a University of Colorado Cancer Center study presented at the American Association for Cancer Research (AACR) Annual Meeting 2019 suggests a way to make irinotecan work even better: When researchers added the experimental drug AZD0156 to irinotecan, colorectal cancer cells and models of human colorectal cancer tumors grown in mice both showed significantly more cancer cell inhibition than with irinotecan used alone. An ongoing phase 1 clinical trial is currently testing the combination against advanced solid tumors (NCT02588105).


Author Cancer Center | Publish Date April 03, 2019
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CU Cancer Center In the News

KDVR

Alarming Trend Shows More Young People Being Diagnosed with Colorectal Cancer

news outletKDVR
Publish DateMarch 28, 2023

While the majority of colorectal cancer cases are still in people over the age of 65, experts said more and more young people are now being diagnosed.

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Cancer Health

Innovative Technology Shows Great Promise Against Certain Mouth and Throat Cancers

news outletCancer Health
Publish DateMarch 20, 2023

An innovative cell squeezing technology showed great promise in a phase I trial against certain head and neck cancers.

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Denver 7

American Cancer Society Says Younger People Are Being Diagnosed with Colon Cancer

news outletDenver 7
Publish DateMarch 16, 2023

Swati Patel, MD, MS, discusses younger people being diagnosed with colon cancer at nearly twice the rate than in 1995.

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CPR

Young People Are Getting Colorectal Cancer, Including This Married Couple

news outletCPR
Publish DateMarch 15, 2023

Doctors increasingly see people contracting colon cancer before the recommended screening age of 45.

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