Sean Ryan did everything right.
Ryan’s father died of colorectal cancer when he was just 45, so Ryan knew he was at high risk for the disease. When he turned 50, he made plans to get a screening colonoscopy. (In 2021, the U.S. Preventive Services Task Force lowered the recommended screening age for colorectal cancer from 50 to 45 for men and women at average risk for colorectal cancer.)