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Department of Biomedical Informatics News and Stories

Clinical decision support (CDS)

Research    Health equity    Clinical Informatics    Clinical decision support (CDS)

AI-Powered Tool Uses Hospital Nursing Notes to Save Lives

For years, David Albers, PhD, associate professor of biomedical informatics at University of Colorado School of Medicine, has been haunted by a friend’s death. It was long before Albers contemplated a career in health care, when he was an undergrad studying physics and taking music lessons in his spare time from accomplished jazz musician Tony Williams.


Author Toni Lapp | Publish Date January 31, 2023
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Department of Biomedical Informatics In the News

Nature

Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms

news outletNature
Publish DateSeptember 13, 2023

Transcriptome-wide association studies have helped uncover the role of individual genes in disease-relevant mechanisms, explain researchers from the CU Department of Biomedical Informatics. However, modern models of the architecture of complex traits predict that gene-gene interactions play a crucial role in disease origin and progression. Researchers introduce PhenoPLIER, a computational approach that maps gene-trait associations and pharmacological perturbation data into a common latent representation for a joint analysis and observe that diseases are significantly associated with gene modules expressed in relevant cell types, and our approach is accurate in predicting known drug-disease pairs and inferring mechanisms of action.

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Health Day

Low-Cal vs. Fasting Diets: How Does Each Affect the Microbiome?

news outletHealth Day
Publish DateAugust 25, 2023

After tracking calorie-control dieters and intermittent fasters for three months, both had improved microbiome diversity, said study author Maggie Stanislawski, an assistant professor in the CU Department of Biomedical Informatics.

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9News

Hate cilantro? It's possible it could be in your genes

news outlet9News
Publish DateAugust 25, 2023

DBMI geneticist Joanne Cole, PhD, explains the role of genetics and other factors in food preference. 

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Nutrients

The Microbiome, Epigenome, and Diet in Adults with Obesity during Behavioral Weight Loss

news outletNutrients
Publish DateAugust 22, 2023

Researchers in the CU Department of Biomedical Informatics evaluate associations among gut microbiota (MB), DNA methylation (DNAme), and diet prior to and during a behavioral weight loss intervention.

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