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Department of Biomedical Informatics News and Stories

Data analysis

DNA    Genetics    Data analysis

What is Genomics?

Genes are at the center of nearly every human disease and symptom, and until the past few decades, medical researchers had a much narrower interpretation of the human body’s entire genetic makeup, also called the genome.

Author Kara Mason | Publish Date August 30, 2023
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Research    Data analysis

CU Data Researchers Connect Diet to Changes in the Microbiome

“Should I be taking a probiotic?” is a question that Maggie Stanislawski, PhD, assistant professor in the University of Colorado Department of Biomedical Informatics (DBMI), gets asked often.  

Author Kara Mason | Publish Date August 17, 2023
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Research    Advancement    Data analysis

Altitude Research Reaches New Heights

Anybody who has ever experienced altitude sickness, even the mildest form known as acute mountain sickness, knows how debilitating it can be. Symptoms, which include lightheadedness, nausea, fatigue, and headache, most often occur at altitudes above 8,000 feet.

Author Kara Mason | Publish Date July 25, 2023
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Research    Rheumatoid Arthritis    Data analysis

CU Data Scientist Receives Funds to Study Precision Medicine for Rheumatoid Arthritis

With no cure or widely successful therapeutic options for patients with rheumatoid arthritis (RA), Fan Zhang, PhD, is looking to computational machine learning to identify new target treatments.

Author Kara Mason | Publish Date July 12, 2023
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Research    Equity Diversity and Inclusion    Data analysis

Researchers Amplify Diverse Sourcing in Science Journalism

Following an analysis of more than 20,000 articles by researchers in the Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, a major science publication is implementing new policies to improve the diversity of its sources.

Author Kara Mason | Publish Date April 05, 2023
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Department of Biomedical Informatics In the News


Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms

news outletNature
Publish DateSeptember 13, 2023

Transcriptome-wide association studies have helped uncover the role of individual genes in disease-relevant mechanisms, explain researchers from the CU Department of Biomedical Informatics. However, modern models of the architecture of complex traits predict that gene-gene interactions play a crucial role in disease origin and progression. Researchers introduce PhenoPLIER, a computational approach that maps gene-trait associations and pharmacological perturbation data into a common latent representation for a joint analysis and observe that diseases are significantly associated with gene modules expressed in relevant cell types, and our approach is accurate in predicting known drug-disease pairs and inferring mechanisms of action.

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Health Day

Low-Cal vs. Fasting Diets: How Does Each Affect the Microbiome?

news outletHealth Day
Publish DateAugust 25, 2023

After tracking calorie-control dieters and intermittent fasters for three months, both had improved microbiome diversity, said study author Maggie Stanislawski, an assistant professor in the CU Department of Biomedical Informatics.

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Hate cilantro? It's possible it could be in your genes

news outlet9News
Publish DateAugust 25, 2023

DBMI geneticist Joanne Cole, PhD, explains the role of genetics and other factors in food preference. 

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The Microbiome, Epigenome, and Diet in Adults with Obesity during Behavioral Weight Loss

news outletNutrients
Publish DateAugust 22, 2023

Researchers in the CU Department of Biomedical Informatics evaluate associations among gut microbiota (MB), DNA methylation (DNAme), and diet prior to and during a behavioral weight loss intervention.

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