New research from Dr. Meghan Jeffres, PharmD, Skaggs School of Pharmacy and Pharmaceutical Sciences, Massachusetts General Hospital (MGH), and University of Porto in Portugal, indicates that most surgical patients with a history of penicillin allergy can safely be given the guideline-recommended antibiotic cefazolin to prevent infection instead of alternative antibiotics that are less effective and more expensive. The researchers reported in JAMA Surgery that the frequency of allergies to both penicillins and cefazolin was so small that most patients should receive cefazolin regardless of their allergy history.
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