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Top 10 Ways You Can Prevent Cancer

Four in 10 cancer cases are preventable. This National Cancer Prevention Month, CU Cancer Center experts weigh in on steps you can take.

5 minute read

by Mark Harden | February 13, 2025
Top 10 Ways You Can Prevent Cancer | CU Cancer Center

The most effective way to fight cancer is to keep it from happening in the first place. And that’s a job for all of us.

About 2 million new cases of cancer were diagnosed in the United States last year, the National Cancer Institute (NCI) estimates. While the overall cancer death rate in the U.S. has declined in recent years, there were about 612,000 cancer deaths in the U.S. last year, the NCI says.

Yet while many cancers are caused by genetics or other uncontrollable risk factors, about four out of 10 cancer cases among adults and roughly half of cancer deaths are preventable, according to American Cancer Society (ACS) research. And mostly, that involves changing habits and making healthy choices. Smoking cigarettes alone is linked to 20% of all U.S. cancer cases and almost 30% of cancer-related deaths, says the American Association for Cancer Research (AACR).

Prevention is part of the core mission of the University of Colorado Cancer Center, Colorado’s only NCI-designated comprehensive cancer center, along with research, education, and world-class multidisciplinary care. The CU Cancer Center’s Cancer Prevention and Control Program applies the expertise of behavioral, basic, and clinician scientists to conduct innovative and impactful cancer research that reduces Colorado’s cancer burden.

Richard Schulick, MD, MBA, director of the CU Cancer Center and chair of the CU Department of Surgery, says there are “three key principles in cancer care: Prevention is best, early detection saves lives, and effective treatment is key. Catching cancer early leads to better outcomes, improved therapy plans, and higher chances of curing.”

February is National Cancer Prevention Month, so here we offer 10 key ways to prevent cancer, drawn from publications of the CU Cancer Center, the NCI, the ACS, the AACR, and other sources.

And to help us understand why these steps are so vital in preventing cancer, we turned to the co-leaders of the Cancer Prevention and Control Program at the CU Cancer Center: Stacy Fischer, MD, professor in the CU Division of General Internal Medicine; and Jamie Studts, PhD, professor in the CU Division of Medical Oncology.

“Prevention is a vital and underutilized piece of the cancer puzzle,” Studts says. “Sometimes behavior change can be hard. But whether it’s changing your diet, increasing your physical activity, applying sunscreen, or reducing other kinds of risks and exposures, it’s the hard stuff that can be very effective.”

The top 10 ways to prevent cancer:

  1. Don’t use tobacco

    Smoking is the leading cause of cancer and many other illnesses, and other tobacco products have also been associated with cancer risk. Quitting smoking improves health and well-being.

    Your Phone Could Help You Hang Up on Smoking

  2. Maintain a healthy weight

    Obesity can increase your risk for at least 13 different types of cancer. Obesity can cause chronic inflammation, which may be an important driver to this risk. And by maintaining a healthy body weight, you can reduce the burden of chronic inflammation.

    ‘Detective’ Works to Crack the Code on How Fat Influences Cancer

  3. Be physically active

    Regular physical activity decreases a broad variety of chronic diseases, including heart disease, diabetes, and cancer. Additional benefits include strengthening bone health, improving mood, and sleep. In older adults, regular exercise helps prevent falls and maintaining independence. Exercise can help improve quality of life across your life span.

  4. Eat healthy foods

    A wide variety of foods, especially a diet rich in fruits and vegetables, provide necessary nutrients and phytochemicals. A healthy diet can also help improve outcomes for chronic conditions such as cardiovascular disease, diabetes, and cancer.

    Dietary Strategies for Preventing Breast Cancer Recurrence

  5. Limit alcohol

    Alcohol is a well-established, preventable cause of cancer responsible for about 100,000 cases of cancer and 20,000 cancer deaths annually in the United States – greater than the 13,500 alcohol-associated traffic crash fatalities per year in the U.S.

    Alcohol is a Leading Cause of Cancer, But Will the Public Heed a New Warning?

  6. Protect yourself from the sun

    Skin cancer is the most common form of cancer, and damaging ultraviolet rays are a major contributor to risk. UV rays are much stronger in Colorado than at lower altitudes. Wearing daily sunscreen with an SPF of at least 30, covering skin with hats and long sleeves, and avoiding the sun between 10 a.m. and 2 p.m. are all important steps to lowering your risk for skin cancer by at least 30-40%.

    Have Fun in the Snow, But Remember: You’ve Got Skin in the Game

  7. Get vaccinated to protect against HPV, hepatitis, and other viral infections

    HPV infection can lead to cervical, head, and neck cancers among others. HPV vaccination can reduce the incidence of these cancers by over 90%. Hepatitis B infection can lead to chronic liver disease and liver cancer. The Hepatitis B vaccine series, when administered to infants, children, and young adults, protects from Hepatitis B infection effectively at least 95% of the time.

    Dramatic Drop in Cervical Cancer Rates is Attributable to Widespread Adoption of HPV Vaccine

  8. Test your home for radon (and mitigate the radon exposure if it is high)

    Naturally-occurring radon is the second leading cause of lung cancer. Testing your home is cheap and easy. Radon mitigation is more costly but is very effective at reducing exposure to radon.

    CU Cancer Center Offers Free Radon Testing Kits to the Colorado Community

  9. Get screened for cancer regularly

    If you are eligible, screening for breast, cervical, colorectal, and lung cancer can help you live longer and healthier. Talking with your health care clinician about screenings that might be good for you is a great way to clarify your cancer screening options.

    What  you need to know about cancer screenings

  10. Be alert for symptoms

    See your primary care provider if you notice unexpected symptoms such as a change in bowel or bladder habits, a sore that does not heal, or a lump in the breast.

Featured Experts
Staff Mention

Richard Schulick, MD, MBA

Staff Mention

Stacy Fischer, MD

Staff Mention

Jamie Studts, PhD