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Cancer study may accidentally help researchers create usable blood stem cells

A massive research effort over more than a quarter century has tried to make personalized blood stem cells for use in treating leukemias, among many other uses. One way researchers have gone about this is to sample a patient’s adult cells and then “deprogram” them to create induced pluripotent stem cells (iPSCs), which are capable of forming any of the body’s cell types, including blood cells. Unfortunately, these iPSCs also have the potential to become cancer. So researchers have largely refocused their efforts on making hematopoietic stem cells (HSCs), which can’t make any cell type, but can produce many types of blood cells. The good news is that HSCs don’t seem to cause cancer like iPCs. The bad news is that researchers have been unable to create HSCs that can take hold and grow in the body.


Author Cancer Center | Publish Date January 16, 2020
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CU Cancer Center In the News

Cure Today

FDA Approves Breyanzi for Previously Treated Large B-Cell Lymphoma

news outletCure Today
Publish DateJune 27, 2022

The FDA approved Breyanzi, a CAR-T cell therapy, for the treatment of certain patients with previously treated large B-cell lymphoma.

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Radiology Business

AI Reads of Neck Ultrasounds Could Displace Thyroid Biopsies

news outletRadiology Business
Publish DateJune 15, 2022

After training a machine learning model to analyze ultrasound images of the neck, researchers tested their algorithm and have found it correctly flagged 97% of likely cancerous nodules of the thyroid gland.

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News Medical

Ultrasound-Based AI Classifier of Thyroid Nodules Can Help Rule Out Cancer, Avoid Unnecessary Biopsies

news outletNews Medical
Publish DateJune 14, 2022

Artificial intelligence (AI) can be used to identify thyroid nodules seen on thyroid ultrasound that are very unlikely to be cancerous, reducing a large number of unnecessary biopsies.

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The Scientist

Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments

news outletThe Scientist
Publish DateMay 31, 2022

A CU Cancer Center researcher recently published a study using DNA from thousands of healthy people to help identify disease-causing mutations by using the principle of natural selection.

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