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CU Cancer Center News and Stories

Blood Cancer

Research    Blood Cancer

CU Cancer Center Members Spotlight the Latest Leukemia Treatments 

Illustrating the University of Colorado Cancer Center’s research strength in the area of blood cancers, the American Cancer Society Journal recently asked CU Cancer Center members Andrew Kent, PhD, and Dan Pollyea, MD, MS, to give readers an update on the latest advances in leukemia treatment.  


Author Greg Glasgow | Publish Date September 11, 2023
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Research    Education    Community    Blood Cancer

Elijah Johnson Came to the CU Cancer Center to Research the Mutation That Makes Him More Likely to Develop Cancer 

Growing up in Windsor, Colorado, Elijah Johnson thought he would grow up to be a professional musician. He never considered a career as a biomedical researcher. But that all changed when his mother was diagnosed with Li-Fraumeni Syndrome (LFS), a rare genetic mutation that increases the risk of cancer.  


Author Greg Glasgow | Publish Date August 30, 2023
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Research    Blood Cancer    Awards

Overcoming Drug Resistance in Multiple Myeloma 

The good news for people with multiple myeloma is that treatments exist that almost always put the cancer into deep remission soon after it’s diagnosed. The bad news for people with the blood cancer, though, is that even though that remission can last several years, almost all patients eventually relapse — and the disease that returns becomes increasingly difficult to treat. 


Author Greg Glasgow | Publish Date June 12, 2023
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Research    Blood Cancer    Immunotherapy    lymphoma

What is the Best Lymphoma Treatment After CAR T Therapy Fails? 

For 30% to 40% of lymphoma patients who receive CAR T therapy, the treatment is a godsend. Typically given to lymphoma patients for whom other treatments have proven ineffective, CAR T therapy involves removing immune cells from the body via a blood draw, reengineering them to become better cancer fighters, then reintroducing them to the bloodstream, where they seek out and destroy cancer cells. 


Author Greg Glasgow | Publish Date April 25, 2023
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Research    Blood Cancer   

Eric Kohler, MD, PhD, Receives Award to Improve CAR T-Cell Therapy 

Already regarded as one of the country’s leaders in CAR T-cell therapy, University of Colorado Cancer Center member M. Eric Kohler, MD, PhD, has received a $150,000 Scholar Award from the American Society of Hematology (ASH) to investigate a method to make CAR T cells function even better. 


Author Greg Glasgow | Publish Date February 24, 2023
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Research    Blood Cancer    Funding   

New Grant Funding Supports Researcher in Understanding Early Factors in Blood Cancer

A necessary part of the scientific process is sometimes being wrong, and Eric Pietras, PhD, was wrong. He’s the first to admit it.

When Pietras, a University of Colorado Cancer Center member and associate professor of hematology, joined the CU School of Medicine in 2015, a significant body of research suggested that inflammation activated blood-forming stem cells, which normally are dormant in bone marrow.


Author Rachel Sauer | Publish Date January 06, 2023
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Community    Blood Cancer    Leukemia    Multiple Myeloma

The Latest on CAR T-Cell Therapy

September is Blood Cancer Awareness Month, a time for bringing attention to leukemia, lymphoma, myeloma, Hodgkin’s disease, and other blood cancers.


Author Greg Glasgow | Publish Date September 16, 2022
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Research    Pediatric Cancer    Blood Cancer    Leukemia    Clinical Trials

St. Baldrick’s Funds CU Study of New Pediatric Leukemia Drug 

As part of its ongoing efforts to eradicate childhood cancers, the St. Baldrick’s Foundation has awarded University of Colorado Cancer Center member Kelly Faulk, MD, a St. Baldrick’s Scholar grant to investigate a new method for treating infant leukemia


Author Greg Glasgow | Publish Date September 08, 2022
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Research    Blood Cancer    Leukemia

New Research Grant Underscores the CU Cancer Center’s Long Relationship With the Leukemia & Lymphoma Society 

In research that reinforces the University of Colorado Cancer Center’s longstanding relationship with the Leukemia & Lymphoma Society (LLS), CU Cancer Center member Lauren Nicholas, PhD, MPP, is co-principal investigator on a new LLS-funded study to examine the role of Medicare plan selection in dealing with a blood cancer diagnosis.  


Author Greg Glasgow | Publish Date August 30, 2022
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Patient Care    Community    Blood Cancer    Colorectal Cancer

Young Colon and Blood Cancer Patient Excited for the Future After Journey Through Treatment and Recovery

Jimmy Guerrero’s first diagnosis was a possible stomach ulcer, because it seemed inconceivable that a 26-year-old would have colon cancer.


Author Rachel Sauer | Publish Date June 13, 2022
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Research    Blood Cancer

New Hope for Patients With Relapsed Large B-cell Lymphoma

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, higher-intensity chemotherapy, followed by a stem cell transplant.


Author Greg Glasgow | Publish Date December 13, 2021
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Press Releases    Pediatric Cancer    Blood Cancer    Brain and Spinal Cancer    Ovarian Cancer

CU Cancer Center Researchers Awarded Grants From V Foundation

Three researchers from the University of Colorado Cancer Center have received grants from the V Foundation, a cancer research nonprofit founded in 1993 by college basketball coach Jimmy Valvano, who died of cancer.


Author Greg Glasgow | Publish Date October 20, 2021
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Community    Blood Cancer

Colin Powell’s Death Highlights the Challenges Multiple Myeloma Patients Face With COVID-19

In a grim reminder of the toll COVID-19 can take even among those who are vaccinated against it, former Secretary of State Colin Powell died Monday of complications from the virus. His family said Powell, who was 84, was fully vaccinated against the disease.


Author Greg Glasgow | Publish Date October 18, 2021
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Blood Cancer    Leukemia

Norm MacDonald’s Death Puts Spotlight on Acute Leukemia

Comedian and former “Saturday Night Live” cast member Norm MacDonald died Tuesday, after what his brother, Neil MacDonald, described as a nine-year battle with acute leukemia. Norm MacDonald, known for his intelligence and sarcastic wit, was 61.


Author Greg Glasgow | Publish Date September 16, 2021
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Research    Blood Cancer

Two Studies by CU Cancer Center Researchers Explore Link Between Inflammation and Leukemia

Two recent collaborative publications by CU Cancer Center members provide insights into how chronic inflammation can serve as a key factor in the development of leukemia and other blood cancers.


Author Valerie Gleaton | Publish Date June 28, 2021
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Research    Honors    Blood Cancer

Effect of Oil and Gas Exposure on Childhood Leukemia Risk Studied by CU Cancer Center Researcher

A pilot study of childhood leukemia patients living near Colorado’s oil and gas drilling sites recently led to an American Cancer Society (ACS) grant award for CU Cancer Center member Lisa McKenzie PhD, MPH.  


Author Valerie Gleaton | Publish Date June 09, 2021
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Patient Care    Blood Cancer    Leukemia    Magazine    Clinical Trials

Acute Myeloid Leukemia (AML) Won’t Slow World Champion Triathlete Down

Siri Lindley couldn’t swim. She had never learned how and the idea of competing in a triathlon seemed completely out of the question.


Author Jessica Cordova | Publish Date May 16, 2021
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Research    Blood Cancer

From Start-Up to Established: Lymphoma Program Celebrates Six Years

When Manali Kamdar, MD, joined the University of Colorado School of Medicine’s Division of Hematology as clinical director of lymphoma services in January 2015, she was fresh off her third fellowship (a bone marrow transplant and lymphoma fellowship at Stanford) and ready for a new challenge.  


Author Valerie Gleaton | Publish Date May 05, 2021
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Research    Pediatric Cancer    Blood Cancer    Leukemia    Magazine

CU Cancer Center Researcher and Physician Poses Double Threat to Pediatric Cancer

M. Eric Kohler’s commitment to both cancer research — particularly CAR T-cell therapy — and clinical care make him a double threat when it comes to battling pediatric blood cancer.   


Author Valerie Gleaton | Publish Date March 26, 2021
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Research    Blood Cancer    Leukemia    Magazine

CU Cancer Center Leukemia Researcher Receives NCI Outstanding Investigator Award

Craig Jordan, PhD, has spent more than 20 years developing better treatments for acute myeloid leukemia (AML), a rapidly progressing cancer of the blood and bone marrow that can spread to other parts of the body, including the lymph nodes, liver, spleen and central nervous system.


Author Greg Glasgow | Publish Date November 23, 2020
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Research    Blood Cancer    Leukemia    Magazine

CU Cancer Center study leads to FDA approval of new treatment for AML

Thanks in large part to early work by investigators at the CU Cancer Center, patients with acute myeloid leukemia (AML) have a new treatment option that has fewer side effects and has been shown to increase longevity.


Author Cancer Center | Publish Date November 10, 2020
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Research    Blood Cancer

CU Cancer Center Effort to Link Underrepresented Patients with Leukemia with Cutting Edge Treatments

A key component in treating newly diagnosed leukemia is genetic and molecular testing. With this knowledge, physicians can better determine which treatment options are best suited for patients based on genetic mutations, fusions and other biologic features. 


Author Cancer Center | Publish Date August 05, 2020
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Research    Blood Cancer    Cancer

CU Cancer Center Researcher Named Pew-Stewart Scholar Aims to Improve Early Cancer Detection

University of Colorado (CU) researcher Srinivas Ramachandran, PhD, was named one of the five 2020 Pew-Stewart Scholars. These researchers are selected to spearhead innovations in cancer research.


Author Cancer Center | Publish Date June 15, 2020
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Research    Blood Cancer    Cancer

Cord blood as source for stem cell transplant may outperform accepted “gold standard” of matched sibling donors

When a blood cancer patient needs a bone marrow transplant, there are four common donor sources: A matched related donor (sibling), a matched unrelated donor (from a donor database), a half-matched donor, or umbilical cord blood. Of course, there are plusses and minuses to each approach, but consensus has generally ranked a matched sibling first, followed by a matched unrelated donor, with cord blood and half-matched donors reserved for patients without either of the first two options. Now a University of Colorado Cancer Center study based on a decade of research and treatment may reshuffle this list. In fact, the comparison of 190 patients receiving cord-blood transplants with 123 patients receiving transplants from the “gold standard” of matched sibling donors showed no difference in survival outcomes between these two approaches, with significantly fewer complications due to chronic graft-versus-host disease in patients receiving transplants from cord blood.


Author Cancer Center | Publish Date June 08, 2020
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Research    Blood Cancer    Non-Hodgkin Lymphoma

Phase III clinical trial results support rituximab as new standard-of-care in pediatric Burkitt lymphoma

Results of the phase III Inter-B-NHL-ritux 2010 clinical trial reported today in the New England Journal of Medicine show 95 percent three-year survival for pediatric patients with advanced B-cell non-Hodgkin lymphoma treated with the addition of anti-cancer immunotherapy rituximab to standard chemotherapy. The trial represents a major international collaboration between the European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) and the Children’s Oncology Group (COG), and was led in the United States by Thomas Gross, MD, PhD, University of Colorado Cancer Center investigator and pediatric oncologist at Children’s Hospital Colorado, and in Europe by Véronique Minard-Colin, MD and Catherine Patte, MD, both pediatric oncologists at the Gustave Roussy Department of Child and Adolescent Oncology in Paris, France. The addition of rituximab decreased treatment failures by 70 percent resulting in a 10 percent increase in the three-year survival rate seen with chemotherapy alone (LMB protocol).


Author Cancer Center | Publish Date June 03, 2020
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Research    Blood Cancer    Cancer

Colorado tool, My-DST, may pick best multiple myeloma treatment

In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question has become what cocktail and sequence is best?


Author Cancer Center | Publish Date May 28, 2020
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Research    Blood Cancer

Lymphoma stage at diagnosis may predict when and where new cancer forms

With improved treatments, especially the use of anti-cancer immunotherapies, more than two-thirds of all patients diagnosed with diffuse large B-cell lymphoma (DLBCL) will survive. However, after treatment, patients are at a small but real risk of developing a new cancer, called a second primary cancer. Now a Colorado study of long term DLBCL survivors shows, for the first time, that the stage at which DLBCL is originally diagnosed impacts the types of second cancers that may form after treatment.


Author Cancer Center | Publish Date October 08, 2019
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CU Cancer Center In the News

MHealthIntelligence

Leveraging RPM to Enable At-Home Care for High-Risk Cancer Patients

news outletMHealthIntelligence
Publish DateFebruary 05, 2024

Glen Peterson, DNP, ACNP, RN, from CU Cancer Center, discusses RPM & telehealth benefits for cancer patients on Healthcare Strategies podcast.

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9News

Sunday is World Cancer Day

news outlet9News
Publish DateFebruary 04, 2024

CU Anschutz oncologist and CU Cancer Center member Dr. Wells Messersmith shares insights: Colorado braces for over 29,000 cancer cases in the coming year.

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Cure Today

An Oncologist Explains How She Uses ctDNA in Gastric Cancer

news outletCure Today
Publish DateJanuary 24, 2024

CU Cancer Center member Sunnie Kim, MD, discussed how she uses ctDNA in treating patients with gastric or esophageal cancer.

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DocWire News

Toxicities and Duration of Treatment for Immunotherapy in Advanced Metastatic Hepatocellular Carcinoma

news outletDocWire News
Publish DateJanuary 23, 2024

CU Cancer Center member Christopher Lieu, MD, and Namrata Vijayvergia, MD, of the Fox Chase Cancer Center conclude their discussion with considerations for managing immunotherapy-related toxicities in patients with metastatic hepatocellular carcinoma (HCC), along with a review of the available evidence regarding the duration of immunotherapy treatment.

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