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CU Cancer Center News and Stories

Clinical Trials

Research    Prostate Cancer    Clinical Trials

New Testosterone Treatment Options for Prostate Cancer Patients

Carlos J. Castro transferred his care to Elizabeth Kessler, MD, University of Colorado Cancer Center member, after learning about a clinical trial that gave him a new treatment option for his stage 4 prostate cancer.


Author Cancer Center | Publish Date January 12, 2022
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Research    Thyroid Cancer    Clinical Research    Clinical Trials

Clinical Trial Experience Motivates Participant to Become Advocate

Tommy Stewart was already a prostate cancer survivor when, during his annual physical in 2004, his physician felt a nodule on his neck.


Author Rachel Sauer | Publish Date October 04, 2021
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Research    Head and Neck Cancer    Clinical Trials

Research Leading to Clinical Trial Testing Two-Armed Approach to Treating Head and Neck Cancer

A crucial challenge in cancer research is figuring out how to make immunotherapies more effective, channeling, and selectively guiding the body’s own immune responses in targeting and killing tumors.


Author Rachel Sauer | Publish Date September 21, 2021
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Patient Care    Lung Cancer    Clinical Trials

Traveling to CU Cancer Center for a Lung Cancer Clinical Trial

David Kooyman transferred his care to University of Colorado Cancer Center member and associate professor of thoracic oncology, Tejas Patil, MD, to be part of a clinical trial to help with his rare lung cancer gene fusion.


Author Cancer Center | Publish Date August 19, 2021
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Research    Patient Care    COVID-19    Clinical Trials

Adjusting to the Virus Has Long-Term Advantages for Clinical Trials

The early days of the COVID-19 pandemic were an adjustment period for medical professionals across the board, but they brought up particular challenges for the Cancer Clinical Trial Office (CCTO) at the University of Colorado Cancer Center. A number of procedures that used to take place in person or in the office — collecting signatures from patients and doctors, delivering medications, submitting data to trial sponsors — suddenly had to be done in a whole new way.


Author Greg Glasgow | Publish Date July 22, 2021
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Research    Patient Care    Esophageal Cancer    Surgical Oncology    Clinical Trials

Investigating a Better Treatment Sequence for Esophageal Cancer

Looking for better ways to treat patients with esophageal cancer, University of Colorado Cancer Center member Martin McCarter, MD, is investigating whether a new treatment sequence will result in better outcomes.


Author Greg Glasgow | Publish Date May 25, 2021
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Patient Care    Blood Cancer    Leukemia    Magazine    Clinical Trials

Acute Myeloid Leukemia (AML) Won’t Slow World Champion Triathlete Down

Siri Lindley couldn’t swim. She had never learned how and the idea of competing in a triathlon seemed completely out of the question.


Author Cancer Center | Publish Date May 16, 2021
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Research    Head and Neck Cancer    Cancer    Clinical Trials

CU Cancer Center Study Aims to Increase Access to Head and Neck Cancer Clinical Trials in Hispanic Population

Nearly two thousand people living in Colorado will be diagnosed with head and neck cancer (HNC) in 2020. Generally, a very aggressive disease, head and neck cancer require expert care that is not widely available in community cancer clinics. However, patients that are not well-represented in clinical studies, especially Hispanic patients, are less likely to get care from centers that specialize in the disease, such as the University of Colorado Cancer Center.


Author Cancer Center | Publish Date June 29, 2020
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Child & Adolescent    Clinical Trials

Study shows fewer kids enrolling in cancer clinical trials

Historically, pediatric cancer patients have been much more likely than adult cancer patients to enroll in clinical trials as part of their treatment. Now a study by University of Colorado Cancer Center researchers working at Children’s Hospital Colorado shows pediatric oncology clinical trial enrollment may be down, from 40-70 percent seen in studies completed in the 1990s, to 20-25 percent in the early 2000s, to 19.9 percent in the current study.


Author Cancer Center | Publish Date April 23, 2020
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Clinical Research    Clinical Trials

With smaller clinical trials, it may be up to doctors to notice rare drug side effects

Tejas Patil, MD, is a medical oncologist. Lisa Ferrigno, MD, MPH, FACS, is a trauma surgeon. Working with lung cancer patients at University of Colorado Cancer Center, they both, independently, noticed something strange: A small percentage of patients taking high doses of the drug osimertinib (Tagrisso) were developing a rare twist in the right side of their colon, a condition called cecal volvulus. Their case series, published in the journal Frontiers in Oncology, describes three of these patients, suggesting that doctors who use osimertinib with EGFR+ non-small cell lung cancer patients may consider watching for rare cases of cecal volvulus along with more expected side effects.


Author Cancer Center | Publish Date April 22, 2020
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Clinical Trials

OnKure and CU Cancer Center announce first patient enrolled in clinical trial of OKI-179, a potent and selective HDAC inhibitor

OnKure, Inc. and the University of Colorado Cancer Center announced enrollment of the first patient in a first-in-human phase 1 clinical trial testing investigational anti-cancer agent OKI-179, a novel and Class-selective HDAC inhibitor, in patients with advanced solid tumors. The study represents a milestone in the ongoing partnership between OnKure and the University of Colorado system, with the drug discovery and development company built around basic research from CU Boulder and the clinical trial taking place in partnership with CU Cancer Center on the Anschutz Medical Campus.


Author Cancer Center | Publish Date June 17, 2019
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Clinical Trials    Radiation

New Investigator Award helps Tyler Robin, MD, PhD bring new clinical trials to Colorado

When Tyler Robin, MD, PhD, graduates from the Radiation Oncology Residency Program at University of Colorado Anschutz Medical Campus at the end of June, he won’t have to move far – after graduation, Robin will make the leap from trainee to researcher, joining CU faculty as an assistant professor in the CU School of Medicine Department of Radiation Oncology where he hopes to be involved with clinical trials testing new uses of radiation as a component of cancer care. A New Investigator Award from the Gynecologic Oncology Group (GOG) and NRG Oncology will help Robin expand the scope of his clinical trial involvement to the national level, while bringing new, innovative clinical trials to cancer patients in Colorado.


Author Cancer Center | Publish Date June 05, 2019
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Clinical Trials    ovarian cancer

ASCO: Phase 1 clinical trials benefit patients with aggressive ovarian cancer

Patients with recurrent, heavily pretreated ovarian cancer generally have few therapeutic options.  Phase 1 clinical trials are considered by some providers as a “last hope.” Historically, there has been concern that there is little clinical benefit to these trials and high concern of toxicity, as these are typically first in human studies. However, these worries may be unnecessary.  A University of Colorado Cancer Center study presented at the American Society of Clinical Oncology (ASCO) conference in Chicago indicates that there are therapeutic benefits for ovarian cancer patients that enroll in Phase 1 clinical trials.  


Author Cancer Center | Publish Date May 30, 2019
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Patient Care    Lung Cancer    Clinical Trials

Virtual clinical trial gives entrectinib edge over crizotinib against ROS1+ non-small cell lung cancer

Crizotinib and entrectinib are both active against ROS1+ non-small cell lung cancer. But which is best? The answer seems easy: Just compare the drugs’ clinical trial results. However, not all trials are created equal, and these differences in trial designs can lead to irrelevant comparisons – like comparing athletes’ running times without noting that one ran a kilometer while the other ran a mile. Now results from an innovative, “virtual” clinical trial presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2019 attempt to place crizotinib and entrectinib on an equal playing field. In this analysis, patients taking entrectinib were able to stay on treatment longer and had about almost 6 months longer progression-free survival than patients treated with crizotinib.


Author Cancer Center | Publish Date May 30, 2019
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Patient Care    Leukemia    Clinical Trials

91 Percent Response Rate for Venetoclax Against Newly Diagnosed AML in Older Adults

Clinical trial results published in the journal Nature Medicine show 91 percent response rate to the combination of venetoclax with azacitidine in older adults newly diagnosed with acute myeloid leukemia (AML). Of 33 patients given combination venetoclax and azacitidine, 20 experienced a complete response (aka complete remission) and eight experienced a complete response but with continued low blood counts. Of the three patients who did not respond to treatment, two discontinued the study before the first week due to personal reasons unrelated to treatment or side-effects.


Author Garth Sundem | Publish Date November 29, 2018
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Patient Care    Brain and Spinal Cancer    Clinical Trials

Drummer Finds New Rhythm after CU Cancer Center Clinical Trial

Bob Rupp is a drummer. He works with the best musicians in the world and he’s celebrated for his contributions to the music scene in the Metro Area. There is even a day in his honor in the City and County of Denver.


Author Erika Matich | Publish Date January 31, 2018
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CU Cancer Center In the News

5280

No, Sun Exposure Is Not the Secret to Living Longer (Probably)

news outlet5280
Publish DateJanuary 05, 2022

CU Cancer Center member Neil Box, MD, separates fact from pseudoscience when it comes to protecting yourself from the sun.

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Denver 7

'I'm Just so Proud of Him': Crested Butte Family Shares 2-year-old's Journey with Kidney Cancer

news outletDenver 7
Publish DateDecember 23, 2021

In 2021, a Crested Butte family received a life-changing diagnosis. During the holiday season, their story is an apparent reminder that sometimes the best gifts are never found under a tree.

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Cure Today

Triplet Regimen Extends Time Before Brain, Spinal Cord Metastases Worsen in Patients with Breast Cancer

news outletCure Today
Publish DateDecember 15, 2021

A three-drug regimen was shown to lengthen the amount of time before cancer progressed to the central nervous system — known as central nervous system progression-free survival — in certain patients with breast cancer.

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Healio

Liso-cel Significantly Improves Outcomes in Second-Line DLBCL

news outletHealio
Publish DateDecember 11, 2021

Second-line lisocabtagene maraleucel more than quadrupled EFS compared with standard therapy for patients with relapsed or refractory large B-cell lymphoma, according to study results presented at ASH Annual Meeting and Exposition.

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