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Blogs

CU Cancer Center News and Stories

Innovation

Research    Innovation

GOAL Consortium Facilitates Group Purchases and Knowledge Sharing for Academic Pathology Testing Labs

When Dara Aisner, MD, PhD, an associate professor in the Department of Pathology at the University of Colorado School of Medicine, was approached by a colleague at another university about splitting the cost of a bulk purchase of new clinical testing products, she initially declined. Although it would be a valuable resource — and might even save her lab money in the long-term — the short-term cost was prohibitive.


Author Valerie Gleaton | Publish Date September 07, 2021
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Innovation    Patient Care    Pancreatic Cancer    Surgical Oncology

Robotic Whipple Procedure Offers Pancreatitis Patient Relief

After suffering from painful bouts of pancreatitis for more than a decade, Christina Gonzalez felt resigned to a seemingly endless cycle of procedures.


Author Valerie Gleaton | Publish Date August 31, 2021
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Innovation    Melanoma

A New Drug Combination to Treat Mucosal Melanomas

Though people most often think of melanoma as affecting the skin, the cancer can occur anywhere in the body where pigment-producing melanocyte cells are found. That includes mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region.


Author Greg Glasgow | Publish Date June 23, 2021
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Research    Innovation

Sean Davis to Lead Health Data Science and AI Efforts for CU Cancer Center

A 13-year veteran of the National Cancer Institute (NCI) is coming to the University of Colorado Cancer Center to help lead efforts to develop and apply data science and artificial intelligence and methods to advance research and improve clinical practice.


Author Greg Glasgow | Publish Date December 30, 2020
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Innovation    COVID-19

CU Mass Spectrometry Shared Resource works to predict embolism in COVID-19

One of the major complications of severe COVID-19 is blood clots in the lungs – a pulmonary embolism that can block lung function leading to death. In fact, these blockages are similar to those from chronic heart disease, stroke, and even traumatic injuries like a car crash or gunshot wound. In these non-COVID-19 conditions, doctors use drugs to break up and dissolve the clotted blood. Now a team led by Colorado trauma surgeon Gene Moore, MD, is testing a similar approach against the dangerous blood clots associated with COVID-19.


Author Cancer Center | Publish Date May 19, 2020
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Research    Innovation

Colorado study overturns ‘snapshot’ model of cell cycle in use since 1974

Cells have a big decision: Should they replicate or sleep? Healthy cells can go either way. Cancer cells’ replication switches are stuck in the ‘on’ position. Now a study by University of Colorado Cancer Center researchers working at CU Boulder’s BioFrontiers Institute and published today in the journal Science overturns the conventional wisdom of how these switches work – a model accepted since 1974 and included in current textbooks. 


Author Cancer Center | Publish Date April 02, 2020
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Research    Innovation

CU Cancer Center project makes big data analysis accessible to Anschutz Campus researchers

Biomedical research can generate big data and it takes big brains running big computers to make any sense of it. For University of Colorado Cancer Center investigators, the solution has been to enlist the bioinformatics expertise provided through the Biostatistics and Bioinformatics Shared Resource (BBSR). Led by Director James Costello, PhD, and Manager/Data Analyst Andrew Goodspeed, PhD, the team of five experts at the BBSR shakes and sifts numbers until meaning emerges. But despite BBSR expertise in data analysis, the researchers generating the data in the first place are often in the best position to define “meaning,” and sending data away for analysis can leave these experts one step removed from their own work. Also, there is only so much shaking and sifting the BBSR can do, leading to a bottleneck in the workflow of research: Data is being generated across the Anschutz Medical Campus faster than investigators can make sense of it.


Author Cancer Center | Publish Date December 05, 2019
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CU Cancer Center In the News

Cure Today

Caring for Patients with Sarcoma is a Team Effort, Expert Says

news outletCure Today
Publish DateJuly 12, 2024

University of Colorado Cancer Center member Dr. Steven Thorpe emphasizes the collaborative nature of treating soft tissue and bone sarcomas, highlighting the multidisciplinary efforts at CU School of Medicine's Department of Orthopedics and Children’s Hospital Colorado. He underscores the goal of not only curing the disease but also preserving function through advanced surgical techniques and modern therapies, ensuring patients maintain quality of life post-treatment. Thorpe stresses the importance of long-term outcomes, tailoring treatments to support patients’ aspirations beyond their cancer journey, especially for pediatric cases.

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OncLive

The Role of mTOR/Aurora A Kinase Combination Therapy Requires Further Elucidation in Solid Tumors

news outletOncLive
Publish DateJuly 08, 2024

CU Cancer Center member S. Lindsey Davis, MD, highlighted that the combination therapy of sapanisertib and alisertib showed marginal clinical benefit for patients with advanced solid tumors, correlative analyses suggested that apoptotic response and tumor immune cell infiltrate might influence clinical outcomes. The phase 1b study's expansion cohort indicated some positive outlying responses among patients and underscore the need for further research to tailor treatments for standout patients and explore rational combinations to enhance efficacy.

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News Medical

Study shows effectiveness of treating pancreatic cancer patients with chemotherapy before surgery

news outletNews Medical
Publish DateJune 19, 2024

A new study led by University of Colorado Cancer Center member Marco Del Chiaro, MD, PhD, reveals that nearly 5% of pancreatic adenocarcinoma patients achieved a pathological complete response (pCR) after pre-surgical chemotherapy or chemoradiotherapy. This significant finding indicates that patients with pCR have a 63% five-year survival rate, compared to 30% for those without pCR, suggesting the potential for tailored treatments to improve outcomes.

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Cancer Network

Liso-cel May Show Benefit in Earlier Therapy Lines for Lymphoma Subgroups

news outletCancer Network
Publish DateJune 14, 2024

In a conversation at the 2024 European Hematology Association Congress, CU Cancer Center member Manali Kamdar, MD, discussed potential future research on lisocabtagene maraleucel (liso-cel; Breyanzi) for mantle cell lymphoma (MCL) and other lymphoma subgroups. She highlighted findings from the phase 1 TRANSCEND NHL 001 trial, noting improved efficacy and safety in patients with fewer prior therapies and non-refractory disease, suggesting liso-cel's utility in earlier treatment lines and specific lymphoma subgroups.

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