Throughout 2025, the Colorado Clinical and Translational Sciences Institute (CCTSI) delivered measurable impact, advancing innovative discoveries into improved health and patient care across Colorado. This work is powered by our strong commitment to training the next generation of translational scientists and research teams statewide.
“For nearly 20 years, CCTSI, primarily supported by a series of National Institutes of Health grants, has provided essential resources, expertise, and facilities for pioneering research,” said Ron Sokol, MD, FAASLD, who has directed the CCTSI since its inception in 2008. “Over the years, we’ve invested in hundreds of early-career researchers, helping them establish themselves as independent investigators.”
In 2025, hundreds of CCTSI members participated in our short courses, workshops, and training programs, including two new offerings: Leading and Teaming in Clinical and Translational Science and Mentoring3.
Key to CCTSI’s mission of supporting clinical investigators, we provide high-quality facilities and specialized resources through our Clinical Translational Research Centers (CTRCs). The CTRCs provide research nursing services, advanced practice providers, cardiovascular bioimaging, nutrition expertise, specialty lab tests, and more. In 2025, more than 500 studies were conducted across our adult and pediatric CTRCs at UCHealth, CU Anschutz, Children’s Hospital Colorado, National Jewish Health, and CU Boulder.
Our 2025 achievements reflect the strength of our partnerships with four universities, five hospitals, and multiple communities across Colorado. The CCTSI annual report features several 2025 key initiatives:
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Advancing innovation and patient care through Pragmatic Electronic Health Record Embedded Trials (PEET). In 2025, the PEET team continued working closely with UCHealth and university leaders to support research studies for patients with prostate cancer, those in critical care settings, and individuals who have an increased risk of falls.
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Hosting the 13th annual CU-CSU Summit at CSU Spur, which focused on novel research approaches to chronic disease causes and treatments. The conference and poster session brought together all partner institutions to present their work and foster collaborations.
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Highlighting CCTSI pilot awards, the ROI of 19 (for every $1 invested in pilot grants, there is a return on investment of more than $19 in follow-on funding), and a feature story on the power and multiple impacts of these grants.
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Showcasing our K12 Scholar and T32 Fellowship Programs and the difference they make for young investigators.
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Giving researchers the opportunity to hone their science communication skills through the workshop series Communicating Your Science to the Public.
“We hope you take a moment to explore the highlights from 2025, which are the result of collaboration across teams, schools, colleges, hospitals, institutions, and communities,” said CCTSI Operations Director Janine Higgins, PhD. “We are deeply grateful for the opportunity to lead the CCTSI and support the biomedical researchers who are driving discovery and improving health and patient care.”
Page 6 and Page 7 of the annual report.
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