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Linda Crnic Institute News and Stories

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Chelsea Donohoe


Research    Clinical Research

Experts Discuss Unique Study Aiming to Help People with Down Syndrome and Chronic Constipation

Down syndrome, also known as trisomy 21, is caused by an extra copy of chromosome 21 and is the most common chromosomal abnormality in the population. Research shows individuals with Down syndrome often experience widespread immune dysregulation and inflammation that can lead to many different co-occurring conditions including issues in the gut. Many are diagnosed with several types of gastrointestinal (GI) motility issues such as celiac disease, irritable bowel syndrome and chronic constipation during their lifetime.


Author Chelsea Donohoe | Publish Date December 12, 2023
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Research    Clinical Research    Equity Diversity and Inclusion    Announcements   

From the Rockies to the Andes and Beyond: A Global Approach to Down Syndrome Research

Down syndrome, also known as trisomy 21, is caused by an extra copy of chromosome 21 and is the most common chromosomal disorder in the human population occurring at an estimated rate of one in every 700 births. The number of babies born with Down syndrome continues to increase and individuals with Down syndrome are living longer than ever. In fact, the average life expectancy for an individual with Down syndrome has increased dramatically from 10 years old in the early 1900s to about 60 years old today.


Author Chelsea Donohoe | Publish Date November 29, 2023
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Research    Press Releases    Funding    Announcements

NIH Funds Study of How Sleep May Be linked to Alzheimer’s Disease in Individuals with Down Syndrome

While it is well known that individuals with Down syndrome have a high risk of developing Alzheimer’s, this population also experiences increased rates of disrupted sleep. A team of scientists at the University of Colorado Boulder believe there may be a genetic link between these conditions.  


Author Chelsea Donohoe | Publish Date November 06, 2023
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Research    Press Releases    Funding

Crnic Institute Scientists Receive $3M in NIH Funding to Develop a Novel  Data Resource for the Study of Down Syndrome

Down syndrome, also known as trisomy 21, is caused by an extra copy of chromosome 21 and is the most common chromosomal abnormality in the human population. While it is known that trisomy 21 changes the genetic make-up of an individual, little is understood about how it affects the structure and function of different organs and tissues across the human body or precisely how these effects contribute to the health issues experienced by individuals with Down syndrome.  


Author Chelsea Donohoe | Publish Date September 29, 2023
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Research    Faculty    Funding

Members of the Crnic Institute Obtain $18M in New Funding from the National Institutes of Health

In the fiscal year 2022, members of the Linda Crnic Institute for Down Syndrome (Crnic Institute) secured more than $18 million in research funding from the National Institutes of Health (NIH). This collaborative group of multidisciplinary researchers includes professionals from across multiple campuses, departments and divisions throughout the University of Colorado system. These funds will support continued research on a wide range of co-occurring conditions affecting individuals with Down syndrome with the explicit goal of elongating the lifespan and improving health outcomes in this underserved population.


Author Chelsea Donohoe | Publish Date September 23, 2022
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