Down syndrome, also known as trisomy 21, is caused by an extra copy of chromosome 21 and is the most common chromosomal abnormality in the population. Research shows individuals with Down syndrome often experience widespread immune dysregulation and inflammation that can lead to many different co-occurring conditions including issues in the gut. Many are diagnosed with several types of gastrointestinal (GI) motility issues such as celiac disease, irritable bowel syndrome and chronic constipation during their lifetime.
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