Research Melanoma Immunotherapy
Melanoma cells can hide, but they can’t run from Eduardo Davila, PhD, associate director of cancer research training and education coordination at the University of Colorado Cancer Center.
Patient Care Community Immunotherapy lymphoma ColoradoSPH at CU Anschutz
For a significant portion of his career, Arnold Levinson, PhD, MJ, has done work related to cancer.
Research Blood Cancer Immunotherapy lymphoma
For 30% to 40% of lymphoma patients who receive CAR T therapy, the treatment is a godsend. Typically given to lymphoma patients for whom other treatments have proven ineffective, CAR T therapy involves removing immune cells from the body via a blood draw, reengineering them to become better cancer fighters, then reintroducing them to the bloodstream, where they seek out and destroy cancer cells.
Research Community Immunotherapy
When it comes to treating cancer, doctors have many tools in their arsenal. For decades, cancer was treated with surgery, chemotherapy and radiation — broad tools that affect healthy cells along with the cancer cells they are meant to eradicate.
Research Patient Care Head and Neck Cancer Clinical Trials Immunotherapy
Jane Hart is a lot of things: extremely proud mom of Shelby, daughter extraordinaire and apple of Jane’s eye. Dog mom to (deservedly spoiled) Maizy, Taco, Winnie, and Walter. Collector of Talavera pottery. Unabashed “Real Housewives of Salt Lake City” fan. A surprising 71, because she looks at least 10 years younger.
Cancer survivor – stage 4 laryngeal cancer that necessitated a tracheostomy and laryngectomy, that forced her to relearn how to breathe and talk.
Head and Neck Cancer Cancer Oncology Immunotherapy
| A promising new study released by the University of Colorado Cancer Center suggests that recurrence of certain cancers can be significantly decreased by irradiating only a select set of lymph nodes near a tumor rather than all of them. |
Patient Care Ovarian Cancer Immunotherapy Genetics
People often tell Winona Williams that she’s brave, and she is. Ovarian cancer could easily become a dark cloud over her, shadowing every minute of every day.
Research Immunotherapy lymphoma
Large B-cell lymphoma (LBCL) is one of the most aggressive lymphomas and accounts for about 30% of all lymphoma diagnoses.
Research Lung Cancer Immunotherapy
An exciting and innovative area of cancer research is immunoprevention, in which studies focus on preventing cancer before its onset by using vaccines, antibodies, and other immune mechanisms.
Patient Care Lung Cancer Prostate Cancer Melanoma Immunotherapy
To understand why Beau Gill built a mental cupboard for Jeff and Spike, first you must travel back with him to the small town of Catemaco in Mexico’s state of Veracruz.
Immunotherapies have revolutionized the care of many cancers, teaching the body’s own immune cells to recognize and attack tumor cells. Leading the way are drugs known as checkpoint inhibitors, which block a kind of “white flag” that tumors wave as a peace signal to T cells that would very much like to kill them. Really, this white flag is a protein called PD-L1 – many tumors coat themselves in it. When PD-L1 on the surface of a cancer cell sees its partner, PD1, on T cells, these T cells are tricked into letting the cancer cell live. To counteract this dirty trick, checkpoint inhibitor drugs block the functions of PD-L1 on tumor cells (e.g. atezolizumab) or PD1 on T cells (e.g. pembrolizumab), allowing T cells to go about their cancer-killing business.
Melanomas tend to be “hot” or “cold” – if they’re hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, and patients with cold tumors tend to show little benefit from immunotherapies. The problem is that it’s been impossible to distinguish a hot melanoma from a cold one – the solution has been to administer immunotherapy and hope for the best, often leading to wasted time and resources. Now a University of Colorado Cancer Center study presented at the American Association for Cancer Research (AACR) Annual Meeting 2019 identifies a possible way to predict which melanomas are hot and cold: Tumors with mutations in genes leading to over-activation of the NF-kB signaling pathway were more than three times as likely to respond to anti-PD1 immunotherapy compared with tumors in which these changes were absent.
Gripped
March 27, 2024
Just 18 months after his leukemia diagnosis and on the brink of a bone marrow transplant, Chen defied the odds with an inspiring ascent. Reflecting on his journey, Chen's resilience shines through as he remains optimistic and determined for the future.
EurekAlert
March 06, 2024
Researchers at the University of Colorado Anschutz Medical Campus found that drugs like botox may slow head and neck cancer progression by targeting nerve interactions in tumor environments, impacting immune responses. This study could lead to new treatments for patients intolerant to traditional therapies.
Mile High Magazine
February 25, 2024
Christopher Lieu, MD speaks on March being Colorectal Cancer Awareness Month and the importance of screening.
National Institutes of Health (NIH)
February 21, 2024
In 2024, the network will launch a pilot study, known as the Vanguard Study on Multi-Cancer Detection, to address the feasibility of using multi-cancer detection (MCD) tests in future randomized controlled trials.
Greg Glasgow
