Research Funding Awards Cell and Gene Therapy
A project to develop a way to boost the effectiveness of cellular cancer therapies, led by the University of Colorado Cancer Center’s Associate Director of Cancer Research Training and Education Coordination, Eduardo Davila, PhD, is one of nine research endeavors by CU School of Medicine faculty members to be awarded major funding from the Anschutz Acceleration Initiative.
A necessary part of the scientific process is sometimes being wrong, and Eric Pietras, PhD, was wrong. He’s the first to admit it.
When Pietras, a University of Colorado Cancer Center member and associate professor of hematology, joined the CU School of Medicine in 2015, a significant body of research suggested that inflammation activated blood-forming stem cells, which normally are dormant in bone marrow.
University of Colorado Cancer Center member Erin Schenk, MD, PhD, has been named one of the CU School of Medicine 2022 Translational Research Scholars and received four-year grant support to facilitate exploration and new lines of research.
A team of scientists and University of Colorado Cancer Center members are collaborating to understand pre-malignancy in lung cancer and decrease the risk of developing the disease, supported by a grant to promote such multi-investigator research.
Research Colorectal Cancer Cancer Funding
When a person has lived with colorectal cancer for a long time, and gotten to the point of not responding to therapies as much or at all, it’s common to develop cachexia. This debilitating condition is a multi-systemic wasting syndrome that can cause weight loss, a loss of muscle and bone mass, fatigue, and frailty.
Three University of Colorado Cancer Center scientists have received a combined total of almost $2 million in grant funding from the American Cancer Society (ACS) to support research addressing a broad spectrum of cancer prevention, diagnosis, and treatment.
Research Support Cancer Funding
University of Colorado Cancer Center researchers from the Anschutz and Boulder campuses are collaborating on a broad range of research that recently received AB Nexus support.
Research Cancer Funding Animal
Four research projects conducted by University of Colorado Cancer Center members from the University of Colorado Anschutz Medical Campus and Colorado State University recently each received $50,000 pilot grant funding from the Joint Pilot Program of the CU Cancer Center and CSU Flint Animal Cancer Center.
Research Breast Cancer Pediatric Cancer Melanoma Funding
The Tumor-Host Interactions Program (THI) at the University of Colorado Cancer Center has awarded four CU Cancer Center researchers $30,000 each to gain preliminary data using the Multiplex Ion Beam Imager (MIBI) housed in the cancer center’s Human Immune Monitoring Shared Resource (HIMSR) to support a competitive national grant proposal. The selected researchers are expected to submit a national competitive grant proposal within six months of completing their THI-MIBI pilot studies.
Research Faculty Pancreatic Cancer Funding
Some battles begin before a shot is even fired, with an army building bridges and grading roads, clearing and smoothing the path to make the invading force stronger and more effective.
Research Honors Head and Neck Cancer Magazine Funding
Research and treatment of head and neck cancers at the University of Colorado Cancer Center reached a new level this month with a highly competitive Specialized Programs of Research Excellence (SPORE) grant from the National Cancer Institute (NCI). The SPORE was approved by NCI Scientific Program leadership for FY2021 funding; the projected starting date is July 1.
Research Faculty Lung Cancer Funding
The American Association for Cancer Research (AACR) announced today that in partnership with the Lung Cancer Initiative at Johnson & Johnson, it will fund a major grant led by University of Colorado Cancer Center investigators to pinpoint the lung tissue characteristics that allow cancer cells to grow, potentially leading to new strategies to prevent and treat the disease.
Cure Today
July 12, 2024
University of Colorado Cancer Center member Dr. Steven Thorpe emphasizes the collaborative nature of treating soft tissue and bone sarcomas, highlighting the multidisciplinary efforts at CU School of Medicine's Department of Orthopedics and Children’s Hospital Colorado. He underscores the goal of not only curing the disease but also preserving function through advanced surgical techniques and modern therapies, ensuring patients maintain quality of life post-treatment. Thorpe stresses the importance of long-term outcomes, tailoring treatments to support patients’ aspirations beyond their cancer journey, especially for pediatric cases.
OncLive
July 08, 2024
CU Cancer Center member S. Lindsey Davis, MD, highlighted that the combination therapy of sapanisertib and alisertib showed marginal clinical benefit for patients with advanced solid tumors, correlative analyses suggested that apoptotic response and tumor immune cell infiltrate might influence clinical outcomes. The phase 1b study's expansion cohort indicated some positive outlying responses among patients and underscore the need for further research to tailor treatments for standout patients and explore rational combinations to enhance efficacy.
News Medical
June 19, 2024
A new study led by University of Colorado Cancer Center member Marco Del Chiaro, MD, PhD, reveals that nearly 5% of pancreatic adenocarcinoma patients achieved a pathological complete response (pCR) after pre-surgical chemotherapy or chemoradiotherapy. This significant finding indicates that patients with pCR have a 63% five-year survival rate, compared to 30% for those without pCR, suggesting the potential for tailored treatments to improve outcomes.
Cancer Network
June 14, 2024
In a conversation at the 2024 European Hematology Association Congress, CU Cancer Center member Manali Kamdar, MD, discussed potential future research on lisocabtagene maraleucel (liso-cel; Breyanzi) for mantle cell lymphoma (MCL) and other lymphoma subgroups. She highlighted findings from the phase 1 TRANSCEND NHL 001 trial, noting improved efficacy and safety in patients with fewer prior therapies and non-refractory disease, suggesting liso-cel's utility in earlier treatment lines and specific lymphoma subgroups.
Mark Harden
